This genetic disorder is associated with constrictive pericarditis. A referenced description can be found in the Online Mendelian Inheritance in Man Database
Results of pericardiectomy. Circulation 2003;107:2810
J Pediatr 1976 Apr;88(4 Pt 1):569-572
Constrictive pericarditis with dwarfism in two siblings (mulibrey nanism).
Cumming GR, Kerr D, Ferguson CC
Two siblings with marked dwarfism, now 11 and 19 years of age, have been followed from infancy. The girl had frequent episodes of pneumonitis and presented at age 4 years with hepatic enlargement and ascites which proved to be due to constrictive pericarditis. The boy presented with growth failure and pseudohydrocephalus. He had fibrous dysplasia of the tibia and a pathologic fracture; acute hepatic congestion followed physical activity at age 13 years and led to the diagnosis of constrictive pericarditis. Muscle function was normal, there was no evidence for a primary liver disorder, and mental development was normal so that the coined word "mulibray" seemed inappropriate. Pericardiectomy produced only partial improvement; both patients have hepatic enlargement and continue to need diuretics. A third patient with dwarfism, frequent respiratory infections, and pericardial calcification has certain features of the syndrome.
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